Chilean-German researchers show impressive effects on the marine ecosystem. Since several decades, plastics dominate many product and packaging sectors. Unfortunately, more and more of these very durable products are polluting our oceans.
Circadian clocks are present in all cells of the body, and have a pervasive influence on all aspects of human physiology. This is because they regulate homeostasis by anticipating rhythmic changes in behavior and nutritional state, and by compartmentalizing incompatible metabolic pathways within precise temporal windows.
For example, it is known that shift workers are particularly susceptible to metabolic diseases such as diabetes. In their recent work, the team led by Uhlenhaut turned their attention to the hour metabolic rhythm of muscles. Building upon previous studies, the scientists studied the synthesis and breakdown of fats and proteins over 24 hours — an approach Fb dating kostenlos might also be interesting for athletes.
In collaboration with Italian and Austrian colleagues from the Venetian Institute of Molecular Medicine and the Universities of Padua, Graz, and Trieste the researchers identified certain processes that are switched on at night by the regulators of the internal clock: At the same time, opposing processes such as fatty acid oxidation and protein breakdown are throttled down, according the authors. These patterns are especially pronounced in the hours before awakening and are thought to prepare the muscles for the day ahead.
In the final Fb dating kostenlos, the scientists investigated possible ways to intervene in these processes. To this end, they examined mice lacking these master regulators.
Without a circadian clock, the animals were leaner, with less fat and more muscle mass. Their hope Fb dating kostenlos that it might be possible to counteract insulin resistance in type 2 diabetes or to stimulate energy use to combat obesity. Original Publication Dyar, K. Transcriptional programming of lipid and Deutscb acid metabolism by the skeletal muscle circadian clock.
To achieve this, it investigates the interaction of genetics, environmental factors and Bekanntscharten. The Institute of Rektlingen Dating seiten brasilien Obesity IDO reuflingen the diseases of the metabolic syndrome by means of systems biological and translational approaches on the basis of cellular systems, genetically modified mouse models and clinical intervention studies. It seeks to discover new signaling pathways in order to develop innovative therapeutic warum männer flirten for the personalized prevention and treatment of obesity, diabetes and their concomitant diseases.
The German Center for Diabetes Research DZD is Fb dating kostenlos national association that brings together experts in the field of diabetes research and combines basic research, translational research, epidemiology and clinical applications.
The aim is to develop novel strategies for personalized prevention and treatment of diabetes. Deutch one of Europe's leading research universities, LMU Munich Deutsch dating kostenlos Bekanntschaften reutlingen committed to kosgenlos highest international standards of excellence in research and teaching. Building on its year-tradition of scholarship, LMU covers a broad spectrum of disciplines, ranging from the humanities and cultural studies through law, economics and social studies to medicine and koxtenlos sciences.
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